Ah well, a few penny's in.
I have had small builder build a house for me, but I knew him, and had previously worked for him - no problems. Did an owner build large Reno, but I had the time - some things never quite got finished.....
So big builders - only use one that you can find a good personal referral for. Good friends of ours have done 3 metricons for instance, but rawson and to a lesser extent McDonald jones seem well finished and designed as well. Most others look terribly cheap to me, but I am not you.
My current Reno is architect and quality builder - both involved from the design process forwards and have worked together previously - this does require trust and money in the bank though.
Do not however owner build - with no experience you have almost no hope of getting it right, and big chance of really stuffing something up, and mores to the point, you will tend to pay too much for labour and supplies. Owner building is not about saving money
It really completely depends on your budget and what you are trying to achieve. Some medium sized builders specialise in new homes and have architects do their design work, but you really need to decide what you want, how much you are prepare to pay for it, then get your nose to the ground and start talking to people you know about builders and projects they have done.
If you were in my home town I could point you clear of a few and towards some others